Pack size: 1 20ml vial  |  Price is for the whole 20ml vial

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Propofol

Form: Injection 10mg/ml

Indication

General anaesthesia, Sedation

Adult Dose

Intravenous Induction and maintenance of general anaesthesia Adult: Induction: 40 mg by inj or infusion every 10 sec. Usual dose: 1.5-2.5 mg/kg. Maintenance: 4-12 mg/kg/hr or intermittent bolus inj of 20-50 mg. Elderly: Including neurosurgical and debilitated patients: Infuse at a rate of 20 mg every 10 sec. Maintenance: 3-6 mg/kg/hr. Usual dose needed: 1-1.5 mg/kg. Sedation Adult: In diagnostic and surgical procedures: Initially, 6-9 mg/kg/hr by infusion given for 3-5 minutes or an alternative dose of 0.5-1 mg/kg by slow inj over 1-5 minutes. Maintenance: 1.5-4.5 mg/kg/hr infusion. Reduce maintenance dose by 20% for high-risk patients needing sedation. For ventilated patients: 0.3-4 mg/kg/hr by infusion. Monitor lipid concentrations if duration of sedation lasts >3 days.

Child Dose

Intravenous Anesthesia Induction 3-16 years: 2.5-3.5 mg/kg IVP over 20-30 sec Maintenance 2 months to 16 years: 0.125-0.3 mg/kg/min IV

Contraindication

Electroconvulsive therapy, obstetrics. Sedation in children <16 yr. Pregnancy, lactation.

Mode of Action

Short-acting, lipophilic sedative/hypnotic; causes global CNS depression, presumably through agonist actions on GABAa receptors.

Precaution

Paediatrics, elderly, hypovolaemia, epilepsy, lipid disorders, patients with increased intracranial pressure. Avoid rapid bolus doses in high risk patients. Emulsion formulation of propofol 2% should only be used in children >3 yr. Lactation: Excreted in breast milk; effect on nursing infant not known

Introduction

__NAME__ is a general anesthetic. It is used in major surgical procedures. It allows the procedures to be carried out without pain and distress. This injection is used in a hospital setting only. __NAME__ is used in general anesthesia. It causes loss of consciousness which is reversible. It is administered under the supervision of a healthcare professional. The most common side effects include headache, vomiting, and nausea. This __NAME__ is safe to use in pregnancy, breastfeeding mothers, patients of liver and kidney disease. Inform your doctor if you are on any medications or have any known allergy to this medicine before the start of the procedure. It is not advised to consume alcohol after you have been administered. Driving should not be done as this medicine may cause sleepiness and may impair your ability to think or react. It is also advised not to operate machinery because of these effects.

Uses of __NAME__

{'list': ['General Anaesthesia']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Nausea', 'Headache', 'Vomiting', 'Local site pain', 'Slow heart rate', 'Decreased blood pressure']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How __NAME__ works

__NAME__ is a general anaesthetic. It works by causing reversible loss of consciousness. This allows surgical procedures to be carried out without pain and distress.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ is safe to use in patients with kidney disease. No dose adjustment of __NAME__ is recommended. However, talk to your doctor if you have any underlying kidney disease. Use of __NAME__ can cause green discoloration of urine.

Safety Advice

__NAME__ is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.