Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Carbidopa + Levodopa

Form: Tablet 25mg+100mg

Indication

Parkinson's disease.

Adult Dose

Parkinson Disease & Parkinson like Disorders Adult: PO: Immediate release: 25 mg/100 mg q8hr or 10 mg/100 mg PO q6-8hr initially; levodopa may be increased by 100 mg/day every 1-2 days Carbidopa should be 70-100 mg/day but not to exceed 200 mg/day; levodopa not to exceed 800 mg/day CR tablet: 50 mg/200 mg PO q12hr initially; may be increased up to 1600 mg/day of levodopa; doses must be given at least 6 hours apart Hepatic impairment: Safety and efficacy not established; use with caution

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment: Safety and efficacy not established; use with caution

Contraindication

Lactation, narrow angle glaucoma, melanoma, psychosis, severely decompensated endocrine.

Mode of Action

Levodopa is the metabolic precurosor of dopamine, it crosses the blood-brain barrier and is converted to dopamine in the brain. Carbidopa increases the amount of levodopa that is transported into the CNS by inhibiting the decarboxylation of peripheral levodopa.

Introduction

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Uses of __NAME__

{'list': ['Parkinson's disease']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Nausea', 'Vomiting', 'Dryness in mouth', 'Constipation', 'Dizziness', 'Sleepiness', 'Headache', 'Abnormal dreams', 'Anxiety', 'Insomnia (difficulty in sleeping)', 'Abnormality of voluntary movements', 'Orthostatic hypotension (sudden lowering of blood pressure on standing)']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ is to be taken empty stomach. Avoid __NAME__ with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How __NAME__ works

__NAME__ is a combination of two medicines: Levodopa and Carbidopa which treats Parkinsonism. Levodopa is a dopamine precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents breakdown of levodopa allowing it to enter the brain and increase dopamine levels.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Partial to complete suppression of lactation was seen in mothers on the treatment with __NAME__, but when the treatment was stopped, lactation returned to normal levels.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. As __NAME__ may cause dizziness, drowsiness, double vision, which may affect your ability to react which may affect your ability to drive.

Safety Advice

__NAME__ is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.