Pack size: Box of 10 Capsules  |  Price is for the whole Box

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Acitretin

Form: Capsule 10mg

Indication

Oral Darier's disease Adult: Initially, 10 mg daily for 2-4 wk. Max: 50 mg/day. Congenital icthyosis Adult: Initially, 25-30 mg daily for 2-4 wk before dose adjustments are done. Usual range: 25-50 mg daily for further 6-8 wk. Max: 75 mg daily for short periods. Severe psoriasis Adult: Initially, 25-30 mg daily for 2-4 wk before dose adjustments are done. Usual range: 25-50 mg daily for further 6-8 wk. Max: 75 mg daily for short periods. Severe lichen planus Adult: Initially, 25-30 mg daily for 2-4 wk before dose adjustments are done. Usual range: 25-50 mg daily for further 6-8 wk. Max: 75 mg daily for short periods.

Administration

Concomitant use with keratolytics or high dose vitamin A. Reduces anticoagulant effect of coumarins e.g. warfarin. Concomitant use of microdised progestin oral contraceptives. Concomitant use of methotrexate can potentiate hepatotoxicty. Concomitant use with tetracycline.

Adult Dose

Female patients to avoid alcohol during and 2 mth after treatment. Avoid blood donation during therapy or at least 1-3 yr after stopping therapy. Children. Radiographic treatment for prolonged therapy. Therapy should not last >6 mth. Monitor plasma lipid and glucose levels (especially diabetics) regularly. Monitor LFTs. Lactation: enters breast milk/not recommended.

Renal Dose

Acitretin is an active metabolite of etretinate but its mechanism of action is unknown.

Mode of Action

Should be taken with food. Take w/ main meals or w/ a glass of milk.

Precaution

Lichen planus, Psoriasis, Congenital icthyosis, Darier's disease

Introduction

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Uses of __NAME__

{'list': ['Psoriasis']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Dry lips', 'Dryness in mouth', 'Skin peeling', 'Joint pain', 'Muscle tightness', 'Cracked lips', 'Itching', 'Change in finger nails', 'Runny nose', 'Nosebleeds', 'Hair loss', 'Increased levels of blood fat']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. __NAME__ is to be taken with food.

How __NAME__ works

__NAME__ is a retinoid. It has a structure similar to vitamin A and is involved in the normal growth of skin cells. It works by stopping overgrowth and thickening of skin cells in psoriasis.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.