Pack size: 1 Tablet  |  Price is for the whole Tablet

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Doxepin

Form: Tablet 3mg

Indication

Anxiety disorders, Depression, Insomnia

Administration

May be taken with or without food.

Adult Dose

Oral Depression/Anxiety Adult: Initiate at low dose (25 mg/day); gradually titrate upward every 5-7 days Dosage range: 25-300 mg/day PO, up to 150 mg/day as single dose If dose exceeds 150 mg/day, divide q12hr Hepatic impairment: Use lower dose and adjust gradually for depression; Insomnia (Silenor) Sleep maintenance 3-6 mg PO within 30 minutes before bedtime; not to exceed 6 mg/day Hepatic impairment/debilitated patients: 3 mg PO within 30 minutes before bedtime Elderly Insomnia Sleep maintenance Starting dose: 3 mg PO within 30 minutes before bedtime May increase to 6 mg PO HS if clinically indicated Depression/Anxiety Lower initial dose (ie, 10 mg/day) and adjust gradually; 10-25 mg PO qHS May increase by 10-25 mg increments q3Day for inpatients and weekly for outpatients if tolerated

Child Dose

<12 years old: Not recommended

Contraindication

Hypersensitivity; mania, glaucoma, neonates (topical); lactation.

Mode of Action

Doxepin inhibits serotonin and norepinephrine re-uptake by the presynaptic neuronal membrane increasing its synaptic conc in the CNS.

Introduction

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Uses of __NAME__

{'list': ['Insomnia', 'Depression', 'Anxiety']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Constipation', 'Difficulty in urination', 'Dryness in mouth', 'Increased heart rate', 'Orthostatic hypotension (sudden lowering of blood pressure on standing)', 'Weight gain']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. The baby should be monitored carefully for excessive sleepiness, and adequate weight gain.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ is safe to use in patients with kidney disease. No dose adjustment of __NAME__ is recommended. However, talk to your doctor if you have any underlying kidney disease.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.