Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Tizanidine

Form: Tablet 2mg

Indication

Spasticity, Painful muscle spasm

Adult Dose

Oral Muscle Spasticity Spasticity associated with multiple sclerosis and spinal cord injury Initial: 2 mg q6-8hr; no more than 3 doses q24hr Maintenance: Increase by 2 to 4 mg until satisfactory response is achieved with minimum 1-4 days between dose increments Not to exceed 36 mg/day Painful muscle spasm associated with musculoskeletal conditions Adult: 2-4 mg tid. Elderly: Not recommended. Hepatic impairment: Avoid or use with extreme caution.

Child Dose

Child < 18 years: Not recommended

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <25 Initially, 2 mg once daily, gradually increasing the dose before increasing the frequency of admin.

Contraindication

Severe hepatic dysfunction.

Mode of Action

Tizanidine, an alpha2-adrenergic agonist, is a centrally acting muscle relaxant structurally related to clonidine. It reduces spasticity by increasing presynaptic inhibition of motor neurons and has no direct effect on skeletal muscle, the neuromuscular junction or on monosynaptic spinal reflexes.

Introduction

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Uses of __NAME__

{'list': ['Muscle relaxation']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Dizziness', 'Sleepiness', 'Dryness in mouth', 'Upset stomach']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

__NAME__ may cause excessive drowsiness with alcohol.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.