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Pyrazone

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৳40.00

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  ৳40.00

Detail Description

Pack size: 1 Tablet  |  Price is for the whole Tablet

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Sulfinpyrazone

Form: Tablet 200mg

Indication

Hyperuricaemia with gout

Administration

Should be taken with food.

Adult Dose

Oral Hyperuricaemia with gout Adult: Initially, 100-200 mg bid, increase gradually over 2-3 wk to 600 mg daily. Maintenance dose (after plasma-urate concentration is controlled): 200 mg daily in divided doses. Max: 800 mg daily. Hepatic impairment: Severe: Avoid.

Renal Dose

Renal impairment: Mild to moderate: Reduce dose. Severe: Contraindicated.

Contraindication

Hypersensitivity to sulfinpyrazone and other pyrazolone derivatives. Patient in whom attacks of asthma, urticaria or acute rhinitis are precipitated by aspirin or other drugs w/ prostaglandin-synthetase inhibiting activity. Acute gout attack, blood coagulation disorders, uric acid renal calculi, porphyria, peptic ulceration, severe parenchymal lesions of liver or kidneys, blood dyscrasias. Severe hepatic and renal impairment. Concomitant use w/ salicylates.

Mode of Action

Sulfinpyrazone increases urinary excretion of uric acid by inhibiting tubular reabsorption of uric acid. It also decreases platelet aggregation.

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Pyrazone
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