Pack size: 1 Injection  |  Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Pralidoxime Chloride

Form: Injection 1gm/vial

Indication

Organophosphorous poisoning, Overdoses of anticholinesterase drugs used in the treatment of, myasthenia gravis.

Administration

IV Preparation Reconstitute by adding 20 mL SWI to the 1 g vial to provide a 50 mg/mL solution (do not use preservative-containing solutions) IV Administration For infusion, dilute required amount of reconstituted solution to 100 mL with NS Infuse over 15-30 min May also be given as 5 min slow IVP IM Administration 1 g vial contents may be reconstituted by adding 3 mL SWI or NS to provide a 300 mg/mL solution

Adult Dose

Organophosphorous Poisoning For IV Infusion: Adults: 1-2 g IV as 15-30 min infusion, repeat a second dose of 1 g to 2 g may be indicated after about one hour if muscle weakness has not been relieved. Additional doses may be given every 10-12 hours if muscle weakness persists. OR Use with atropine, which affects muscarinic receptors; pralidoxime's actions most striking at nicotonic sites (increase muscle strength 10-40 min) For IV Injection: For fluid restricted patient 1 g, should be slowly given (over not less than 5 minutes) by IV injection, as 50 mg/ml solution in normal saline (e.g. 1 g in 20 ml). IM: 600 mg IM x3 doses; administer each dose 15 minutes apart for mild symptoms, or in rapid succession for severe symptoms Acetylcholinesterase Inhibitor Toxicity Initial: 30 mg/kg IV (IM, SC if no IV access) over 20 min 4-8 mg/kg/hr IV infusion

Child Dose

$4a

Renal Dose

Renal Impairment: Reduce dose

Contraindication

Carbamate pesticide poisoning, hypersensitivity.

Introduction

__NAME__ is a prescription medicine used in the treatment of poisoning caused by pesticides and chemicals that contain organophosphates. It is used in the cases where respiratory depression occurs as a result of muscle weakness due to poisoning. __NAME__ is administered in a medical emergency situation thus aim should be to seek treatment of poisoning without waiting for the results of laboratory tests. This injection is given under the supervision of a healthcare professional. Moreover, it is important to consult your doctor if you have abnormal heartbeat, difficulty or trouble with breathing, increased muscle weakness, or severe tiredness after receiving this medicine. There can be some side effects like nausea, muscle weakness, headache, double vision, and blurred vision. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you will better. This medicine may also increase your blood pressure, so it is better to consult your doctor if it bothers you.

Uses of __NAME__

{'list': ['Organophosphate poisoning']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Accomodation disorder', 'Dizziness', 'Double vision', 'Drowsiness', 'Headache', 'High blood pressure', 'Increased heart rate', 'Muscle weakness', 'Nausea']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ reactivates the enzymes blocked by many pesticides (organophosphates). It is an antidote used in the poisoning of these pesticides.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, please consult your doctor.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Safety Advice

It is not known whether __NAME__ alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

There is limited information available on the use of __NAME__ in patients with liver disease. Please consult your doctor.