Pack size: 1 Tablet  |  Price is for the whole Tablet

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Palonosetron

Form: Tablet 0.5mg

Indication

Chemotherapy-induced nausea and vomiting, Postoperative nausea and vomiting

Administration

Reconstitution: Physically and chemically stable at concentrations of 5 and 30 mcg/ml in glucose 5%, sodium chloride 0.9%, glucose 5% in lactated Ringer's for at least 48 hr at room temperature, exposed to light and for 14 days under refridgeration. IV Administration Flush IV line with NS before and after administration CINV: give IVP evenly over 30 sec (adults) or 15 min (children) PONV: IVP over 10 sec

Adult Dose

Prevention of Chemotherapy-induced Nausea & Vomiting Intravenous Adult: 0.25 mg IV as a single dose. To be given over 30 sec and 30 minutes before chemotherapy. Do not repeat within 7 days. Oral Alternatively 0.5 mg tablet/capsule approximately 1 hour before the start of chemotherapy. Then 0.5 mg tablet once daily. Prevention of Postoperative Nausea & Vomiting Adult: 0.075 mg IV as a single dose immediately before induction of anaesthesia. Hepatic impairment: Dose adjustment not necessary

Child Dose

Prevention of Postoperative Nausea & Vomiting <18 years: Safety and efficacy not established Prevention of Chemotherapy-induced Nausea & Vomiting <1 month: Safety and efficacy not established 1 month to 17 years: 20 mcg/kg IV infused over 15 minutes x1, beginning 30 minutes before chemotherapy; not to exceed 1.5 mg/dose

Renal Dose

Renal impairment: Dose adjustment not necessary

Contraindication

History of hypersensitivity.

Introduction

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Uses of __NAME__

{'list': ['Nausea', 'Vomiting']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Headache', 'Constipation']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Do not handle the tablets with wet hands. Put it in your mouth but do not swallow it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ is safe to use in patients with kidney disease. No dose adjustment of __NAME__ is recommended.

Safety Advice

__NAME__ is safe to use in patients with liver disease. No dose adjustment of __NAME__ is recommended.