Pack size: 1 0.4ml pre-filled syr  |  Price is for the whole 0.4ml pre-filled syr

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Enoxaparin Sodium

Form: Injection 40mg/0.4ml

Indication

Myocardial infarction, Unstable angina, Venous thromboembolism, Deep vein thrombosis

Administration

Low body weight (<45 kg for women or <57 kg for men): Increased exposure has been observed with prophylactic (non-weight adjusted) dosage; carefully monitor for sign/symptoms of bleeding Administer deep SC alternating right and left anterior and posterior abdominal walls into skin fold held between thumb and forefinger Use of tuberculin syringe (or equivalent) is recommended to assure appropriate measurement of dose For IV administration, may administer in IV line with 0.9% NaCl or D5W

Adult Dose

$4c

Renal Dose

Renal impairment Severe (CrCl <30 mL/min): Dosage reductions required Prophylaxis in abdominal surgery: 30 mg SC qDay Prophylaxis in hip or knee replacement surgery: 30 mg SC qDay Prophylaxis in medical patients with restricted mobility: 30 mg SC qDay DVT treatment (inpatient or outpatient) coadministered with warfarin: 1 mg/kg SC qDay Non-Q-wave myocardial infarction: 1 mg/kg SC qDay Treatment of acute STEMI (<75 years): 30 mg IV single bolus plus 1 mg/kg SC, THEN 1 mg/kg SC qDay Treatment of acute STEMI (>75 years): No initial bolus; maintenance of 1 mg/kg SC qDay

Contraindication

Hyper-sensitivity to either Enoxaparin, heparin or other low molecular weight heparins; major clotting disorders like history of thrombocytopenia, active gastro-intestinal ulcer or organic lesion likely to bleed, recent haemorrhagic vascular cerebral stroke. Although rare, cutaneous or systemic allergic reactions may occur.

Mode of Action

Enoxaparin is a low molecular weight heparin w/ anticoagulant properties. It acts by enhancing the inhibition rate of activated clotting factors including thrombin and factor Xa through its action on antithrombin III.