Napa 500mg Tablet

Introduction

Napa 500mg is a widely used medication for relieving pain and reducing fever. It is effective for conditions such as:

• Headache

• Toothache

• Muscle and joint pain

• Common cold

• Osteoarthritis and other types of arthritis

It contains paracetamol (also known as acetaminophen), which is both an analgesic (pain reliever) and antipyretic (fever reducer).

Uses of Napa

• Fever

• Mild to moderate pain

• Osteoarthritis and rheumatoid arthritis

• Migraine

• Postoperative pain

• Neuropathic pain

• Chronic low back pain

• Renal stone pain

Dosage & Administration

Adults

• Tablets: 1–2 tablets every 4–6 hours. Max 4 g (8 tablets) per day.

• Extended-Release (XR): 2 tablets every 6–8 hours. Max 6 tablets/day.

• Syrup/Suspension: 4–8 measuring spoonful's 3–4 times daily.

• Suppository: 500 mg–1 g every 4–6 hours. Max 4 g/day.

Children

• 6–12 years: ½ to 1 tablet 3–4 times daily.

• Syrup:

  • 2 months: 60 mg

  • 3 months–<1 year: 60–120 mg

  • 1–5 years: 1–2 spoonful's

  • 6–12 years: 2–4 spoonful's

• XR Tablets (12+ years): Same as adults.

Note: Always follow your doctor's instructions for the exact dose.

How to Take Napa

• Take with food or milk to prevent stomach upset.

• Swallow whole; do not chew or crush.

• If you miss a dose, take it as soon as you remember—unless it’s nearly time for your next dose. Do not double up on doses.

How Napa Works

• Analgesic: Blocks pain signals in the nervous system.

• Antipyretic: Regulates the body’s temperature via the hypothalamus.

• Weak anti-inflammatory action via reduced prostaglandin synthesis in the CNS.

Side Effects

Common

• Generally well-tolerated when taken as directed.

Occasional

• Nausea

• Vomiting

• Stomach pain

Rare but Serious

• Liver damage (especially with overdose or alcohol use)

• Blood disorders: Thrombocytopenia, leukopenia

• Severe skin reactions: Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis

• Kidney damage in long-term use

Contraindications

• Known hypersensitivity to paracetamol

• Severe liver disease

Precautions

• Use caution in patients with:

  • Liver or kidney impairment

  • Chronic alcohol use

  • G6PD deficiency

  • Malnutrition or dehydration

• During pregnancy and lactation, use only if prescribed.

• Avoid alcohol during treatment to reduce liver risk.

Interactions

• Increased effect with:

  • Probenecid

  • Chloramphenicol

• Decreased absorption with:

  • Cholestyramine (if taken within 1 hour)

• Altered effect with:

  • Anticonvulsants (e.g., phenytoin, carbamazepine)

  • Warfarin (increased bleeding risk with long-term use)

• Enhanced absorption with:

  • Metoclopramide, domperidone

• May cause severe hypothermia with phenothiazines

Quick Tips

• Do not exceed the recommended dose.

• Avoid combining with other paracetamol-containing medicines.

• Check with your doctor if using for more than a few days.

• Regular monitoring may be required for long-term use.