Moov 1%

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Detail Description

Pack size: 1 10gm tube | Price is for the whole 10gm tube

Generic: Diclofenac Sodium 1% Topical

Form: Gel 1%

Indication

Rheumatoid arthritis, Osteoarthritis, Joint and muscular pains

Administration

Apply to clean, dry skin Avoid showering/bathing until gel/solution is dry for at least 30 min Wash hands after use Avoid clothing on knees until gel/solution is dry

Adult Dose

Topical/Cutaneous Osteoarthritis Adult: Apply 2 g (upper extremities)/4 g (lower extremities) q6hr Not to exceed 8 g/day to any single joint of (upper) extremities; 16 g/day to any single joint of (lower extremities) Local symptomatic relief of pain and inflammation Adult: As diclofenac Na (1% gel): Apply onto affected area 3 or 4 times daily.

Child Dose

Safety and efficacy not established

Contraindication

Contraindicated to the patients hypersensitive to any ingredient of the products. Diclofenac is also contra-indicated in asthmatic patient in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor. Gel should not be used under occlusive airtight dressings.

Mode of Action

Diclofenac, a phenylacetic acid derivative is a prototypical NSAID. It has potent anti-inflammatory, analgesic and antipyretic actions. Inhibits cyclooxygenase (COX)-1 and COX-2, thereby inhibiting prostaglandin synthesis. May also inhibit neutrophil aggregation/activation, inhibit chemotaxis, decrease proinflammatory cytokine level, and alter lymphocyte activity.