Pack size: 1 Tablet  |  Price is for the whole Tablet

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Megestrol Acetate

Form: Tablet 160mg

Indication

Contraception, Breast carcinoma, Endometrial carcinoma, Anorexia and Cachexia

Administration

Should be taken with food.

Adult Dose

Oral Palliative treatment of breast carcinoma Adult: 40 mg 4 times daily or 160 mg once daily. Palliative treatment of endometrial carcinoma Adult: 40-320 mg daily in divided doses. evaluate efficacy after 2 months of treatment; up to 800 mg/day may be used Anorexia and cachexia in patients with cancer or AIDS Adult: Initial: 800 mg daily. Usual range: 400-800 mg daily.

Renal Dose

Renal impairment: Use with caution; in normal renal function, 57-78% is excreted in urine within 10 days

Contraindication

Pregnancy and lactation. Severe hepatic impairment.

Mode of Action

Megestrol is a progestogen used as an antineplastic and appetite stimulant. The mechanism of it's antineoplastic effects is not known but may be due to inhibition of oestrogen synthesis, modulation of other steroid hormones and/or a direct cytotoxic effect on tumour cells.

Introduction

__NAME__ is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV. __NAME__ should be taken with or without food, preferably at a fixed time each day to ensure consistent levels of medicine in the body. This medicine is not used for pregnant or breastfeeding women. It may cause side effects like high blood pressure and increased blood sugar levels but they are temporary. However, if these persists, consult with the doctor.

Uses of __NAME__

{'list': ['Breast cancer', 'Endometrial cancer']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Increased appetite', 'Weight gain', 'Hot flashes', 'High blood pressure', 'Constipation', 'Increased glucose level in blood']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is a progestin (female hormone). It works in patients with breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It causes weight gain by increasing appetite.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ does not usually affect your ability to drive.

Safety Advice

__NAME__ should be used with caution in patients with severe kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with severe liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.