Pack size: Strip of 4 Capsules  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Esomeprazole + Amoxicillin + Clarithromycin Kit

Form: capsule 20mg+500mg+500mg

Indication

Eradication of H. pylori, in active chronic gastric,duodenal and gastric ulcers.

Adult Dose

Oral Each strip contain one Esomeprazole USP 20mg capsule, two Amoxicillin BP 500mg tablets and one Clarithromycin USP 500mg tablet Each strip twice daily for 7-14 days

Contraindication

Contraindicated in patients with known hypersensitivity to any of its compo-nent.

Mode of Action

Amoxicillin: Inhibits bacterial cell wall synthesis by binding to one or more penicillin binding proteins that in turn inhibit the final transpeptidation step of peptoglycan synthesis in cell wall biosynthesis. Clarithromycin: Inhibits protein synthesis by binding to 50S ribosomal subunit causing antibacterial activity. Esomeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in the gastric parietal cell.

Precaution

Serious and occasionally fatal hypersensitivity reactions have been reported in patients on Amoxicillin therapy. These reactions are more apt to occur in indivduals with a history of penicillin hypersensitivity. Clarithromycin should not used in pregnant women except in clinical circumstances where no alternative is appropriate.

Side Effect

Common adverse reactions included diarrhoea and nausea. >10% Clarithromycin GI effects, general (13%) 1-10% Clarithromycin Headache (6%),Rash (children 3%),Abdominal pain (adults 2%, children 3%),Abnormal taste (adults 3-7%),Diarrhea (3-6%),Dyspepsia (2%),Heartburn (adults 2%),GI intolerance (oral-dose related),Nausea (adults 3-6%),Vomiting (adults 1%; children 6%),Decreased WBC, elevated BUN (4%), elevated PT (1%) Esomeprazole >10% Headache (2-11%) 1-10% Flatulence (10%),Indigestion (6%),Nausea (6%),Abdominal pain (1-6%),Diarrhea (2-4%),Xerostomia (3-4%),Dizziness (2-3%),Constipation (2-3%),Somnolence (1-2%),Pruritus (1%) Frequency Not Defined Amoxicillin Headache,Rash,Diarrhea, nausea, vomiting,Anemia,AST/ALT elevation,Acute exanthematous pustulosis,Exfoliative dermatitis Seizure,Insomnia,Hemorrhagic colitis,Toxic epidermal necrolysis,Urticaria,Stevens-Johnson syndrome,Anaphylaxis,Candidiasis (mucocutaneous), pseudomembranous colitis, serum sickness

Introduction

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Uses of __NAME__

{'list': ['Peptic ulcer disease']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Nausea', 'Diarrhea', 'Vomiting', 'Stomach pain', 'Taste change', 'Flatulence', 'Headache', 'Rash']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Check the label before use. __NAME__ is to be taken empty stomach.

How __NAME__ works

__NAME__ is a combination of three medicines: Amoxycillin, Clarithromycin and Esomeprazole, which treats stomach/intestinal ulcers caused by the bacteria. Amoxycillin is an antibiotic which works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Clarithromycin is also an antibiotic which stops bacterial growth by preventing the synthesis of essential proteins required by the bacteria to carry out vital functions. Together, they eradicate your infection effectively. Esomeprazole is a proton pump inhibitor (PPI) which reduces the amount of acid in the stomach and relieves acid-related indigestion and heartburn.

Safety Advice

Caution is advised when consuming alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. __NAME__ can have side effects and the symptoms (such as allergic reactions, dizziness and convulsions) may make you unfit to drive.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.