Pack size: 1 5ml drop  |  Price is for the whole 5ml drop

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Loteprednol Etabonate 0.5% + Tobramycin 0.3% Eye prep

Form: Eye Drop 0.5%+0.3%

Indication

Keratitis, Allergic conjunctivitis, Iritis, Ocular inflammation, Bacterial ocular infection, Cyclitis

Adult Dose

Ocular Inflammation Indicated for steroid-responsive ocular inflammations with risk of superficial bacterial infections Adult: Instill 1 or 2 drops of into the conjunctival sac of the affected eye(s) every 4 to 6 hours.; may use as frequently as q1-2hr during first 24-48 hr Decrease frequency of administration as signs and symptoms improve

Child Dose

Safety & efficacy not been established.

Contraindication

Hypersensitivity to any component of the formulation or to other corticosteroids Viral, mycobacterial & fungal eye infections

Mode of Action

Loteprednol is a synthetic nonfluorinated glucocorticoid. It stimulates the production of lipicortins, proteins that modulate the activity of prostaglandins and leukotrienes. Tobramycin acts by binding to 30S ribosomal subunits thus interfering with bacterial protein synthesis. It is active against many aerobic gram-negative bacteria and some aerobic gram-positive bacteria but inactive against Chlamydia, fungi, viruses, and most anaerobic bacteria.

Precaution

History of herpes simplex infections May exacerbate infections by nonsusceptible organisms Monitor IOP if used >10 d Bacterial keratitis reported from inadvertent contamination of multiple dose ophthalmic solution Immunosuppression resulting from prolonged use of steroid use may result in secondary bacterial and fungal infections; steroids may also mask symptoms of infections and enhance existing ocular infections Ocular hypertension and/or glaucoma reported with prolonged corticosteroid use Discontinue use if sensitivity reaction to tobramycin develops Corticosteroid use following cataract surgery may delay healing Lactation: Excretion in milk unknown; use caution

Introduction

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Uses of __NAME__

{'list': ['Eye infection with inflammation']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Eye irritation', 'Eye discomfort']}

How to use __NAME__

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

How __NAME__ works

__NAME__ is a combination of two medicines: Loteprednol etabonate and Tobramycin. Loteprednol etabonate is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen and itchy. Tobramycin is an antibiotic. It stops bacterial growth in the eye by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

Safety Advice

No interaction found/established

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. To reduce the amount of __NAME__ that reaches the breastmilk, place pressure over the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Safety Advice

__NAME__ may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.

Safety Advice

No interaction found/established

Safety Advice

No interaction found/established