Pack size: 1 Injection  |  Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Trastuzumab

Form: Injection 440mg/20ml

Indication

Breast cancer, Gastric cancer

Administration

IV Administration Not for IV push or bolus administration Administer initial IV infusion over 90 min Subsequent weekly IV infusions may be administered over 30 min if prior infusions are well tolerated

Adult Dose

$4b

Child Dose

Safety and efficacy not established

Contraindication

Lactation (start only 6 mth after last dose of drug). Do not admin by rapid IV or bolus inj.

Mode of Action

Trastuzumab, a monoclonal antibody, has action directed against a cell surface protein produced by human epidermal growth factor receptor 2 (HER2). It inhibits proliferation of tumour cells that overexpress HER2 e.g. in 1/3 of breast cancer.

Introduction

$4c

Uses of __NAME__

{'list': ['Breast cancer', 'Stomach cancer']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Anemia (low number of red blood cells)', 'Chills', 'Common cold', 'Cough', 'Decreased blood cells (red cells, white cells, and platelets)', 'Diarrhea', 'Fatigue', 'Fever', 'Headache', 'Heart failure', 'Infection', 'Insomnia (difficulty in sleeping)', 'Mucosal inflammation', 'Nausea', 'Rash', 'Stomatitis (Inflammation of the mouth)', 'Taste change', 'Upper respiratory tract infection', 'Weight loss']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, please consult your doctor.

Safety Advice

__NAME__ may cause excessive drowsiness with alcohol.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

It is not known whether __NAME__ alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Safety Advice

__NAME__ is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.

Safety Advice

There is limited information available on the use of __NAME__ in patients with liver disease. Please consult your doctor.