Pack size: 1 Tablet  |  Price is for the whole Tablet

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Gefitinib

Form: Tablet 250mg

Indication

Non-small Cell Lung Cancer

Administration

Film-coated tab: May be taken with or without food. May also be dispersed in ½ glass of plain, non-carbonated water. No other liqd should be used. Drop the tab in water & stir w/o crushing until it disperses (approx 10 min). Drink immediately. Rinse glass w/ another ½ glass of water & drink. Dispersed liqd may also be administered via NG tube.

Adult Dose

Oral Locally advanced or metastatic non-small cell lung carcinoma Adult: 250 mg once daily until disease progression or unacceptable toxicity

Contraindication

Hypersensitivity. Lactation.

Mode of Action

Gefitinib is a synthetic anilinoquinazoline which inhibits the intracellular phosphorylation of numerous tyrosine kinases associated w/ transmembrane cell surface receptors found on both normal and cancer cells, including epidermal growth factor receptor (EGFR) tyrosine kinase. Tyrosine kinase activity appears to be essentially important to cell proliferation and survival.

Precaution

Patients w/ concurrent idiopathic pulmonary fibrosis, acute onset or worsening pulmonary or eye symptoms. Renal and hepatic impairment. Pregnancy. Monitoring Parameters Monitor liver function, prothrombin time or INR frequently. Lactation Unknown if distributed in human breast milk; not recommended

Introduction

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Uses of __NAME__

{'list': ['Non-small cell lung cancer']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Diarrhea', 'Dry skin', 'Loss of appetite', 'Nausea', 'Rash', 'Stomatitis (Inflammation of the mouth)', 'Vomiting', 'Weakness']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, skip it and continue with your normal schedule. Do not double the dose.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. __NAME__ may make you feel weak. This may affect your driving ability.

Safety Advice

__NAME__ should be used with caution in patients with severe kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.