Generic: Sodium Alginate Sodium Bicarbonate Calcium Carbonate  |  Dosage Form: Chewable Tablet  |  Manufacturer: Reckitt & Benckiser Ltd.

Indications

This preparation is indicated in-

• Gastric reflux
• Heartburn
• Indigestion
• Flatulence associated with gastric reflux
• Heartburn of pregnancy
• All cases of epigastric and retrosternal distress where the underlying cause is gastric reflux.

Dosage & Administration

For oral suspension:

• Adult and children over 12 years:10-20 mL after meals and at bedtime, up to four times a day.
• Children 6 to 12 years: 5-10 mL after meals and at bedtime, up to four times a day.
• Children under 6 years: Not recommended.
• Elderly: No dose modifications necessary.

Chewable Tablet should be taken in oral route after being thoroughly chewed. Recommended dose:

• Adults and children 12 years and over: Take two to four tablets after meals and at bedtime, up to four times a day.
• Children under 12 years: Tablets should be given only on medical advice.

Hepatic Impairment: No dose modification necessary.
Renal Insufficiency: Caution if highly restricted salt diet is necessary.

Interaction

A time-interval of 2 hours should be considered between this drug intake and the administration of other medicinal products, especially Tetracyclines, Digoxine, Fluoroquinolone, Iron salt, Ketoconazole, Neuroleptics, Thyroid Hormones, Penicillamine, beta-blockers (Atenolol, Metoprolol, Propranolol), Glucocorticoid, Chloroquine and Biphosphonates (diphosphonates) and Estramustine.

Contraindications

This product is contraindicated in patients with known or suspected hypersensitivity to the active ingredients or to any of the excipients.

Side Effects

In addition to the desired effect of the drug, some side effects may appear such as: constipation, flatulence, stomach cramp or belching. In these cases consult a physician. If too big dose has been taken, there might appear a sensation of swelling. In this case, it is advisable to consult a physician.

Precautions & Warnings

Each 20 ml of dose has a sodium content of 254.5 mg (11.06 mmol). This should be taken into account when a highly restricted salt diet is recommended, e.g. in some cases of congestive cardiac failure and renal impairment.

Each 20 ml contains 260 mg (6.5 mmol) of calcium. Care needs to be taken in treating patients with hypercalcaemia, nephrocalcinosis, and recurrent calcium containing renal calculi.

Treatment of children younger than 12 years of age is not generally recommended, except on medical advice.

This combination is considered high in sodium. This should be taken into account when a highly restricted salt diet is recommended, e.g., in some cases of congestive cardiac failure and renal impairment. Each tablet contains 75 mg of calcium. Care needs to be taken in treating patients with hypercalcaemia, nephrocalcinosis and recurrent calcium containing renal calculi. Due to its aspartame content this combination should not be given to patients with phenylketonuria. If symptoms persist, or treatment is required for more than 7 days continuously, medical advice should be sought. Taking this combination can mask the symptoms of other more serious, underlying medical conditions. It should not be used in patients with impaired renal function/insufficiency and with hypophosphatemia. This may cause allergic reactions.

Overdose Effects

In the event of over dosage symptomatic treatment should be given. The patient may notice abdominal distension.

Therapeutic Class

Antacids

Storage Conditions

Store in a cool (below 30°C) and dry place, away from light. Keep out of the reach of children. Do not refrigerate or freeze.