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Detail Description

Pack size: 1 Injection  |  Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Esomeprazole Sodium Injection

Form: Injection 40mg/vial

Indication

Heartburn, Acid Related Dyspepsia, Peptic ulcer disease, Zollinger-Ellison syndrome, Gastroesophageal reflux disease (GERD), Helicobacter pylori infection, Erosive Esophagitis, Gouty arthritis.

Administration

Reconstitution: Each single-use vial contains 20 or 40 mg of esomeprazole. For IV inj: Reconstitute each vial w/ 5 mL of normal saline and consume w/in 12 hr. For IV infusion: Reconstitute each vial w/ 5 mL of normal saline, lactated Ringer's inj or dextrose 5% inj, then further dilute the resultant solution to a final volume of 50 mL. IV Administration IV injection Injection: Over no less than 3 min Intermittent IV infusion Infuse over 10-30 min regardless of amount Flush IV line with NS, LR, or D5W prior to and after administration Do not administer with any other drugs Continuous IV infusion Administer initial 80 mg IV dose over 30 min, THEN follow with Continuous IV infusion of 8 mg/hr for total treatment duration of 72 hr

Adult Dose

Intravenous Gastro-oesophageal reflux disease Adult: 20 or 40 mg by inj over at least 3 min or infusion over 10-30 min once daily for <10 days. Convert to oral therapy as soon as possible. NSAID-associated ulceration Adult: 20 mg/day by inj over at least 3 min or infusion over 10-30 min. Convert to oral therapy as soon as possible. Gastric and duodenal ulcers Adult: 80 mg infusion over 30 min followed by continuous infusion of 8 mg/hr over 72 hr, then convert to oral therapy given as 40 mg once daily for 4 wk. Elderly: No dosage adjustment needed. Hepatic impairment: Severe (Child-Pugh class C): <20 mg/day.

Child Dose

Short-term Treatment of GERD IV Short-term treatment of GERD with erosive esophagitis when oral therapy is not possible or appropriate <1 month: Safety and efficacy not established 1 month to 1 year: 0.5 mg/kg IV qDay >1 year (<55 kg): 10 mg IV qDay >1 year (?55 kg): 20 mg IV qDay

Renal Dose

Renal impairment: No dosage adjustment needed.

Contraindication

Esomeprazole is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted Benzimidazoles.

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