Pack size: 1 Injection  |  Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Filgrastim

Form: Injection 300mcg/0.5ml

Indication

Myelosuppressive chemotherapy, Acute Myeloid Leukemia, receiving induction or consolidation chemotherapy, Peripheral blood progenitor cell collection and therapy, Severe Neutropenia, Bone marrow transplantation, HIV infection.

Administration

IV Preparation Vials may be diluted in D5W to >15 mcg/mL for infusion 5-15 mcg/mL dilution: Protect from adsorption to plastic materials by the addition of human albumin to a final concentration of 2 mg/mL Do not dilute with saline at any time, because the product may precipitate IV Administration Short IV infusion over 15-30 min, OR Continuous IV infusion SC Administration Administer undiluted by SC in the outer area of upper arms, abdomen, thighs, or upper outer areas of the buttock

Adult Dose

$4b

Contraindication

Hypersensitivity to E. coli derived proteins, Filgrastim or any component of the product. Myeloid malignancies. Not to be used within 24 hr of cytotoxic chemotherapy admin due to the sensitivity of rapidly dividing myeloid cells. Severe congenital neutropaenia (Kostman's syndrome) with abnormal cytogenetics.

Mode of Action

Filgrastim is a granulocyte-colony stimulating factor which binds to cell surface receptors on haemetopoietic cells thus stimulating the development of granulocytes to increase their migration and cytotoxicity.

Precaution

Filgrastim should not be administered within 24 hours before and after chemotherapy. Premalignant or malignant myeloid condition; sickle-cell disease; osteoporotic bone disease; withdraw treatment if there are signs of pulmonary infiltrates. Fluid retention or heart failure. Monitor CBC and platelet count during therapy. Monitor bone density in patients with osteoporosis (long-term treatment). Regular morphological and cytogenic bone-marrow examinations in severe congenital neutropenia. Pregnancy and lactation. Lactation: excretion in milk unknown; use with caution

Introduction

$4d

Uses of __NAME__

{'list': ['Infections after chemotherapy']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Bone pain', 'Weakness', 'Headache', 'Rash', 'Nausea', 'Increased lactate dehydrogenase level in blood', 'Vomiting', 'Increased uric acid level in blood', 'Oropharyngeal pain', 'Hair loss', 'Fatigue', 'Diarrhea', 'Constipation', 'Decreased appetite', 'Cough', 'Breathing problems']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

What if you forget to take __NAME__?

If you miss a dose of __NAME__, please consult your doctor.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. __NAME__ may cause fatigue. This may affect your driving ability.

Safety Advice

__NAME__ is safe to use in patients with kidney disease. No dose adjustment of __NAME__ is recommended.

Safety Advice

__NAME__ is safe to use in patients with liver disease. No dose adjustment of __NAME__ is recommended.