Pack size: 1 5ml pre-filled syrin  |  Price is for the whole 5ml pre-filled syrin

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Fulvestrant

Form: Injection 250mg/5ml

Indication

Metastatic breast cancer, in postmenopausal women w/ oestrogen-receptor positive tumours.

Adult Dose

Intramuscular Metastatic breast cancer in postmenopausal women with oestrogen-receptor positive tumours Adult: 500 mg (250 mg into each buttock) on days 1, 15, and 29, then once monthly thereafter. Moderate (Child-Pugh Class B): 250 mg (into 1 buttock) on days 1, 15, and 29, then once monthly thereafter. Severe: Contraindicated.

Renal Dose

Renal impairment Negligible amounts of fulvestrant are eliminated in urine In clinical trials, fulvestrant concentrations in women with eCrCl ?30 mL/min were similar to women with normal creatinine

Contraindication

Pregnancy and lactation.

Mode of Action

Fulvestrant competitively binds to oestrogen receptors, forming a nuclear complex, leading to down-regulation of oestrogen receptor protein levels and inhibition of tumour growth.

Precaution

Patient w/ bleeding diatheses, thrombocytopenia. Admin at dorsogluteal inj site. Mild to moderate hepatic and severe renal (CrCl <30 mL/min) impairment.

Introduction

$4b

Uses of __NAME__

{'list': ['Breast cancer']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Headache', 'Vomiting', 'Weakness', 'Allergic reaction', 'Nausea', 'Injection site reaction', 'Urinary tract infection', 'Diarrhea']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ blocks the action of estrogen on breast cancer cells. This can lower or stop the growth of some breast cancer cells that need estrogen to grow.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, please consult your doctor.

Safety Advice

Caution is advised when consuming alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Safety Advice

__NAME__ does not usually affect your ability to drive.

Safety Advice

__NAME__ should be used with caution in patients with severe kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Limited information is available on the use of __NAME__ in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.