Pack size: 1 Injection  |  Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Phenytoin Sodium

Form: Injection 50mg

Indication

Epilepsy, Tonic-clonic status epilepticus

Administration

IV Preparation Load IV in 250 mL NS; monitor BP IV/IM Administration Administer slowly; no more than 50 mg/min in adults and no more than 1-3 mg/kg/min in pediatric patients

Adult Dose

Status epilepticus Load 10-15 mg/kg or 15-20 mg/kg at 25-50 mg/min, THEN Maintenance: 100 mg IV q6-8hr PRN Administer IV slowly; not to exceed 50 mg/min

Child Dose

Status Epilepticus 15-20 mg/kg IV in single or divided dose; if necessary may administer additional dose of 5-10 mg/kg 10 min after loading dose Maintenance: 4-8 mg/kg/day IV divided twice daily

Contraindication

Pregnancy. IV admin in sinus bradycardia, heart block, or Stokes-Adams syndrome.

Mode of Action

Phenytoin acts as an anticonvulsant by increasing efflux or decreasing influx of sodium ions across cell membranes in the motor cortex during generation of nerve impulses; thus stabilising neuronal membranes and decreasing seizure activity. It acts as an antiarrhythmic by extending the effective refractory period and suppressing ventricular pacemaker automaticity, shortening action potential in the heart.

Introduction

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Uses of __NAME__

{'list': ['Epilepsy/Seizures']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Rash', 'Headache', 'Dizziness', 'Vomiting', 'Nausea', 'Slurred speech', 'Vertigo', 'Confusion', 'Nervousness', 'Constipation', 'Tremor', 'Altered walking']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Please consult your doctor.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.