Eburn

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Overview
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Detail Description

Pack size: 1 25gm tube | Price is for the whole 25gm tube

Generic: Silver Sulfadiazine

Form: Cream 1%

Indication

Cuts, Wounds, Severe burns, Post-operative wound dressing, Bed sores

Administration

$48

Adult Dose

Topical/Cutaneous Treatment and prophylaxis of infection in severe burns Adult: Apply onto affected area 1-2 times/day.

Child Dose

Burn Wound Infections (2°/3°) <2 months: Contraindicated >2 months (1% cream): Apply onto affected area 1-2 times/day.

Contraindication

Silver sulfadiazine cream is contraindicated in patients known to be hypersensitivity to silver sulphonamide or to other components of the preparation such as cetyl alcohol or propylene glycol. Because sulphonamide therapy is known to increase the possibility of kernicterus, silver sulphadiazine cream should not be used in pregnant women at term, in premature infants or in infants during the first months of life. It should not be used if hepatic and renal functions become impaired or if the condition of porphyria is suspected.

Mode of Action

Silver sulfadiazine has broad antimicrobial activity; it is active against gram-positive and gram-negative bacteria as well as some yeasts and fungi. The silver salt acts mainly on the cell wall and membrane to disrupt its intergrity thus allowing it to impair the essential enzymes, bacterial DNA and RNA leading to cell death.