Pack size: 1 Tablet  |  Price is for the whole Tablet

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Lercanidipine Hydrochloride

Form: Tablet 10mg

Indication

Mild to moderate essential hypertension, Stroke prevention.

Administration

Should be taken on an empty stomach. Take on an empty stomach at least 15 min before meals.

Adult Dose

Oral Hypertension Adult: As hydrochloride: 10 mg once daily, increased after 2 wk to 20 mg daily if necessary. Elderly: The recommended dosage is 10 mg orally once a day at least 15 minutes before meals; the dose may be increased to 20 mg depending on the individual patient's response. Hepatic impairment: Special care should be exercised in patients with mild to moderate renal or hepatic dysfunction. Dosage above 20 mg daily must be approached with caution. Lercanidipine is not recommended for use in patients with severe hepatic dysfunction.

Renal Dose

Renal impairment: Dosage may need to be reduced in mild to moderate renal impairment. Avoid in patients with CrCl <12 ml/min.

Contraindication

Severe hepatic or renal impairment; aortic stenosis, unstable angina, uncontrolled heart failure, within 1 mth of MI; and known hypersensitivity to any dihydropyridine. Lercanidipine should not be taken with grapefruit juice. lactation, pregnancy.

Mode of Action

Lercanidipine is a dihydropyridine calcium-channel blocker which acts by inhibiting the influx of calcium ions through the slow channels of the vascular smooth muscle and myocardium during depolarization. Its main effect is vasodilatation because it has greater selectivity for vascular smooth muscle than cardiac smooth muscle.

Introduction

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Uses of __NAME__

{'list': ['Hypertension (high blood pressure)']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Dizziness', 'Edema (swelling)', 'Fatigue', 'Flushing (sense of warmth in the face, ears, neck and trunk)', 'Headache', 'Palpitations']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ is to be taken empty stomach.

How __NAME__ works

__NAME__ is a calcium channel blocker. It regulates the blood pressure by relaxing the blood vessels and reducing the pressure on them, thereby making it easier for the heart to pump more blood throughout the body. In this way, it treats to normalize the blood pressure in patients with high blood pressure.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

Caution is advised when consuming alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not recommended in patients with severe kidney disease.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not recommended in patients with severe liver disease.