Pack size: 1 4ml Vial  |  Price is for the whole 4ml Vial

Generic: Daunorubicin

Form: Injection 20mg/4ml

Indication

Acute leukaemia, AIDS-related Kaposi's sarcoma

Administration

IV Preparation Reconstitute 20 mg vial with 4 mL SWI to a final concentration of 5 mg/mL IV Administration Vesicant, never administer IM or SC IVP: desired dose is withdrawn into a syringe containing 10-15 mL NS, then injected over 2-3 min into the tubing or sidearm of a freely flowing IV infusion of NS or D5W Has also been diluted in 100 mL of D5W or NS & infused over 30-45 min Flush with 5-10 mL of IV solution before & after drug administration

Adult Dose

Acute Nonlymphocytic Leukemia In combination with cytarabine 100 mg/m²/day IV for 7 days first course, for 5 days subsequent courses <60 years old: 45 mg/m² IVP days 1, 2, 3 first course; days 1, 2 subsequent courses >60 years old: 30 mg/m² IVP days 1, 2, 3 first course; days 1, 2 subsequent courses Acute Lymphocytic Leukemia 45 mg/m² IVP days 1, 2, 3 Hepatic Impairment < 1.2 mg/dL serum bilirubin: Dose adjustment not necessary 1.2-3 mg/dL serum bilirubin: 75% of regular dose > 3 mg/dL serum bilirubin: 50% of regular dose

Child Dose

Acute Nonlymphocytic Leukemia <2 years old or <0.5 m² BSA: 1 mg/kg IVP qWeek >2 years old or >0.5 m² BSA: 25 mg/m² IVP qWeek Acute Lymphocytic Leukemia <2 years old or <0.5 m² BSA: 1 mg/kg IVP qWeek >2 years old or >0.5 m² BSA: 25 mg/m² IVP qWeek

Renal Dose

Renal Impairment >3 mg/dL serum creatinine: Administer 50% regular dose

Contraindication

Heart failure. Pregnancy, lactation.

Introduction

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Uses of __NAME__

{'list': ['Blood cancer']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Nausea', 'Vomiting', 'Low blood platelets', 'Ulcer', 'Abdominal pain', 'Loss of appetite', 'Decreased white blood cell count', 'Hair loss', 'Fever', 'Decreased blood cells (red cells, white cells, and platelets)', 'Fatigue', 'Anemia (low number of red blood cells)', 'Chills', 'Diarrhea', 'Mucosal inflammation', 'Febrile neutropenia', 'Stomatitis (Inflammation of the mouth)', 'Breathing problems']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not recommended in patients with severe kidney disease.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not recommended in patients with severe liver disease.