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Detail Description

Pack size: 1 100ml bot  |  Price is for the whole 100ml bot

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Guaiphenesin + Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride

Form: Syrup (30mg+100mg+1.25mg)/5ml

Indication

Pneumonia, Productive cough, Allergic rhinitis, Sneezing, Respiratory tract disorders, Cough & runny nose, Nasal congestion

Adult Dose

Adult: 10 ml (2 teaspoonful) three times a day.

Child Dose

Children over 12 years: 10 ml (2 teaspoonful) three times a day. Children 6-12 years: 5 ml (1 teaspoonful) three times a day. Children 2-5 years: 2.5 ml (1/2 teaspoonful) three times a day.

Contraindication

Patients with a known hypersensitivity to guaiphenesin, psedoephedrine or triprolidine. Contraindicated in persons under treatment with monoamine oxidase inhibitors within 2 weeks of stopping such treatment. Patients with severe hypertension or severe coronary artery disease

Mode of Action

Triprolidine hydrochloride is a potent competitive histamine H1-receptor antagonist with antimuscarinic and mild sedative properties. Pseudoephedrine is both an alpha-and beta-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa. It also directly stimulates beta-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility. Guaifenesin increases the volume and reduce the viscosity of tenacious sputum and is used as an expectorant for productive cough.

Precaution

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