Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Bisoprolol + Amlodipine

Form: Tablet 2.5mg+5mg

Indication

Treatment of mild to moderate hypertension

Adult Dose

Oral Adult 1 tablet once daily

Contraindication

Cardiogenic shock, overt cardiac failure, second or third degree AV block, and marked sinus bradycardia and known sensitivity to amlodipine/bisoprolol.

Mode of Action

Bisoprolol selectively and competitively blocks β1-receptors but has little or no effect on β2-receptors except at high doses. Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina.

Precaution

Bisoprolol: Overt congestive cardiac failure, abrupt cessation of therapy, peripheral vascular disease, bronchospastic disease, anesthesia and major surgery, diabetes and hypoglycaemia and thyrotoxicosis. Amlodipine: Severe aortic stenosis, congestive heart failure and hepatic failure This medicine is not recommended for use in breastfeeding women unless absolutely necessary.

Side Effect

Edema, headache, increase heart rate, sneezing, fatigue, leg cramps, dry mouth. Other adverse events reported were gastric irritation, angina, asthma, cold extremities, cough, decrease in libido, dizziness, facial flushing, postural hypotension, skin rash, sleep disturbance and vertigo.

Introduction

__NAME__ is used to treat hypertension (high blood pressure). This is a combination of two medicines that controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke. "__NAME__ is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that effectively controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke. It should be taken empty stomach preferably in the morning at a fixed time every day. This medicine should not be stopped abruptly as it may result in sudden increase of blood pressure. It should be used along with a proper diet, salt restriction, and regular exercise for best results. Some patients may develop swelling of ankle as a side effect of this medicine. It may also produce dizziness initially, but this improves with time. "

Uses of __NAME__

{'list': ['Hypertension (high blood pressure)']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Sleepiness', 'Headache', 'Ankle swelling', 'Flushing (sense of warmth in the face, ears, neck and trunk)', 'Slow heart rate', 'Tiredness', 'Palpitations', 'Nausea', 'Edema (swelling)', 'Constipation', 'Cold extremities']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is a combination of two medicines: Amlodipine and Bisoprolol, which lowers blood pressure effectively. Amlodipine is a calcium channel blocker which works by relaxing blood vessels while bisoprolol is a beta blocker that works specifically on the heart to slow down the heart rate. Together, they make the heart more efficient at pumping blood throughout the body.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Regular blood pressure monitoring is advisable for dose adjustment.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. __NAME__ is started at a lower dose in these patients and further increased slowly with careful monitoring.