Brexpa 1 (Strip of 10)

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৳150.00

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Overview
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Detail Description

Pack size: Strip of 10 Tablets | Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Brexpiprazole

Form: Tablet 1mg

Indication

Indicated for schizophrenia, Indicated as adjunctive treatment for major depressive disorder

Administration

May take with or without food

Adult Dose

Schizophrenia Indicated for schizophrenia Recommended starting dose: 1 mg PO qDay on Days 1 through 4 Recommended target dose: 2-4 mg PO qDay; titrate to 2 mg qDay on Days 5 through 7, and then to 4 mg/day on Day 8 based on the patient’s clinical response and tolerability Not to exceed 4 mg/day Periodically reassess to determine the continued need and appropriate dose Depression Indicated as adjunctive treatment for major depressive disorder Recommended starting dose: 0.5 mg or 1 mg PO qDay Recommended target dose: 2 mg PO qDay; at weekly intervals, titrate to 1 mg/day, and then up to 2 mg/day Titrate according to clinical response and tolerability Not to exceed 3 mg/day Periodically reassess to determine the continued need and appropriate dose Hepatic impairment Moderate-to-severe hepatic impairment (Child-Pugh ?7) MDD: Not to exceed 2 mg/day Schizophrenia: Not to exceed 3 mg/day

Renal Dose

Renal impairment Moderate, severe, or ESRD (CrCl <60 mL/min) MDD: Not to exceed 2 mg/day Schizophrenia: Not to exceed 3 mg/day

Contraindication

Hypersensitivity; reactions have included rash, facial swelling, urticaria, and angioedema

Mode of Action

Serotonin-dopamine activity modulator (SDAM) that acts as a partial agonist at 5-HT1A and dopamine D2 receptors at similar potency, and an antagonist at 5-HT2A and noradrenaline alpha1B/2C receptors