Pack size: 1 5ml drop  |  Price is for the whole 5ml drop

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep

Form: Eye Drop 0.2%+0.5%

Indication

Open-angle glaucoma, Ocular hypertension

Adult Dose

Adult: Ophth: Instill 1 drop 2 times/day approximately 12 hours apart.

Contraindication

Hypersensitivity. Patients receiving MAO inhibitor therapy.

Mode of Action

Brimonidine is an alpha 2-adrenoceptor agonist which works to reduce aqueous humor production and increase uveoscleral flow. Timolol is a non-selective beta-adrenergic receptor blocker. It does not have significant intrinsic sympathomimetic activity, direct myocardial depressant activity or local anaesth activity. Exact mechanism of ocular hypotensive effect is unclear, but it is thought to be related to reduction of aqueous humour formation. beta-blockade also causes lowering of BP.

Precaution

Patients wearing soft contact lenses should wait for at least 15 min after instilling brimonidine tartrate before inserting soft contact lenses. Renal or hepatic impairment. CV disease. Use with caution in patients with depression, cerebral or coronary insufficiency, Raynaud's phenomenon, orthostatic hypotension or thromboangitis obliterans. Pregnancy, lactation. Lactation: use caution

Side Effect

5-15% Allergic conjunctivitis,Conjunctival folliculosis,Conjunctival hyperemia,Eye pruritus,Ocular burning,Stinging 1-5% Asthenia,Blepharitis,Corneal erosion,Depression,Epiphora,Eye discharge,Eye dryness,Eye irritation,Eye pain,Eyelid edema,Eyelid erythema,Eyelid pruritus,Foreign body sensation,Headache,Hypertension,Oral dryness,Somnolence,Superficial punctate keratitis,Visual disturbance

Introduction

$49

Uses of __NAME__

{'list': ['Ocular hypertension', 'Glaucoma']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Itching', 'Stinging sensation', 'Foreign body sensation', 'Burning sensation in eye', 'Eye redness', 'Blurred vision', 'Tiredness', 'Drowsiness', 'Headache', 'Dryness in mouth']}

How to use __NAME__

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

How __NAME__ works

__NAME__ is a combination of two medicines: Timolol and Brimonidine. Timolol is a beta blocker while Brimonidine is a sympathomimetic. They work by decreasing the production of aqueous humor (fluid in the eye), thereby lowering the increased eye pressure.

Safety Advice

No interaction found/established

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. To reduce the amount of __NAME__ that reaches the breastmilk, place pressure over the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. __NAME__ may cause blurred or abnormal vision. This effect may seem worse at night or in reduced lighting and this may affect the ability to drive.

Safety Advice

No interaction found/established

Safety Advice

No interaction found/established