Pack size: 1 Injection  |  Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Rituximab

Form: Injection 500mg/10ml

Indication

Non-Hodgkin's lymphoma; follicular lymphoma

Administration

Reconstitution: Dilute the appropriate dose w/ sodium chloride 0.9% or glucose 5% to a final concentration of between 1 and 4 mg/mL. IV Administration Consider premedication (ie, paracetamol and diphenhydramine, or glucocorticoids for RA) before each infusion Administer by slow IV infusion only; do not administer as an IV First IV infusion rate: Start 50 mg/hr; increase by 50 mg/hr q30min, not to exceed 400 mg/hr Subsequent IV infusions (90 minutes) Standard IV infusions: Start 100 mg/hr, increase by 100 mg/hr q30min, not to exceed 400 mg/hr; institutional protocols may allow faster increments

Adult Dose

$4b

Child Dose

Safety and efficacy not established

Contraindication

Lactation. Type I hypersensitivity or anaphylactic reactions to murine proteins or component of the formulation.

Mode of Action

Rituximab is a chimeric monoclonal antibody to CD20 antigen which regulates cell cycle initiation. It binds to the antigen on the cell surface, activating complement-dependent B-cell cytotoxicity; and to human Fc receptors, mediating cell killing through an antibody-dependent cellular toxicity.

Introduction

$4d

Uses of __NAME__

{'list': ['Non-Hodgkin lymphoma (NHL)', 'Rheumatoid arthritis', 'Blood cancer (Chronic lymphocytic leukemia)', 'Granulomatosis with polyangiitis', 'Microscopic polyangiitis']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Headache', 'Weakness', 'Edema (swelling)', 'Infection', 'Hair loss', 'Itching', 'Chills', 'Febrile neutropenia', 'Decreased white blood cell count (neutrophils)', 'Infusion reaction', 'Increased risk of infection', 'Decreased blood cells (red cells, white cells, and platelets)']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, please consult your doctor.

Safety Advice

Caution is advised when consuming alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Safety Advice

It is not known whether __NAME__ alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Safety Advice

__NAME__ is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.

Safety Advice

There is limited information available on the use of __NAME__ in patients with liver disease. Please consult your doctor. Use of __NAME__ is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.