Pack size: Box of 16 Tablets  |  Price is for the whole Box

Generic: Paracetamol + Phenylephrine + Guaifenesin

Form: Tablet 250mg+100mg+5mg

Indication

Temporary Relief of Sinus Congestion, Headache, Minor Aches & Pains

Adult Dose

Temporary Relief of Sinus Congestion, Headache, Minor Aches & Pains 2 tabs PO q4hr; not to exceed 12 tabs/24hr; not to exceed 1g/hr or 4g/day of Paracetamol 30 mL [(325mg/5mg/200mg)/15mL] PO q4hr 20 mL [(162.5mg/5mg/2.5mg/100mg)/5mL] PO q4hr

Child Dose

>12 years 2 tabs PO q4hr; not to exceed 12 tabs/24hr; not to exceed 1g/hr or 4g/day of Paracetamol 30 mL [(325mg/5mg/200mg)/15mL] PO q4hr 20 mL [(162.5mg/5mg/2.5mg/100mg)/5mL] PO q4hr

Contraindication

Hypersensitivity G-6-PD deficiency Severe hepatotoxicity

Mode of Action

Paracetamol blocks pain impulse generation peripherally & may inhibit the generation of prostaglandin in the CNS; reduces fever by inhibiting the hypothalamic heat-regulating center Phenylephrine is a vasoconstrictor and decongestant that relieves symptoms resulting from irritation of upper respiratory tract tissue; shrinks swollen mucous membranes, reduces nasal congestion and tissue hyperemia Guaifenesin increases respiratory tract fluid secretions and helps to loosen phlegm and bronchial secretions.

Precaution

Phenylephrine: Caution in elderly patients, hyperthyroidism, myocardial disease, bradycardia, partial heart block or severe arteriosclerosis Paracetamol: Hepatotoxicity possible in chronic alcoholics following various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; contained in many OTC products and combined use with these products may result in toxicity due to cumulative doses exceeding recommended maximum dose Paracetamol: Risk for rare, but serious skin reactions that can be fatal; these reactions include Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP); symptoms may include skin redness, blisters and rash Guaifenesin: not for administration in persistent cough associated with chronic bronchitis, smoking, asthma, or accompanied with excessive secretions